aGuangdong Key Laboratory for Diagnosis & Treatment of Emerging Infectious Diseases bShenzhen Key Laboratory of Infection & Immunity, Shenzhen Third People's Hospital, Guangdong Medical College, Shenzhen cState Key Laboratory of Chinese Medicine Powder and Medicine Innovation in Hunan (incubation), Division of Stem Cell Regulation and Application, Hunan University of Chinese Medicine, Hunan, China dDepartment of Medical Microbiology, Immunology, & Cell Biology, Simmons Cooper Cancer Institute, Southern Illinois University School of Medicine, Springfield, Illinois, USA.